Case report of ankylosing spondylitis
male patient with atypical onset stiffness
Keywords:
Ankylosing spondylitis, HLA-B 27, Spinal stiffnessAbstract
Ankylosing spondylitis is a spondyloarthropathy characterized by chronic and indolent inflammation of the axial skeleton.2,3 In cases of severe disease, it can lead to fusion and stiffening of the spine. In AD, the spinal nerves are affected, generating pain and also bone calcification that exceeds the intervertebral discs, thus creating a bone bridge causing what is known as a bamboo column.4 Rheumatic pathology is of unknown origin, occurs more frequently in young men and is strongly associated with the HLA-B 27 genetic marker.3 Treatment must be done through physical activities, physiotherapy and also with drugs, such as anti-inflammatories and biological remedies. special for rheumatic disease. 2,3 This case study shows how a 24-year-old Brazilian patient, born in Rio de Janeiro, Brazil, was diagnosed at 17 years of age with ankylosing spondylitis, his vertebral calcifications started in reverse than usual, his symptoms and treatments, as well as the etiology of monogenetic disease that may or may not manifest with the presence of antigen.
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Copyright (c) 2023 Fábio Da Paz Pereira, Sara Viera Rodríguez, Joana D’arc Costa Belfort, Sthéphanny Da Silva Saldanha, Rebeca Gomes Targino de Souza, Giomar Melo de Almeida Londe
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